p38 MAPK-IN-1

Name: p38 MAPK-IN-1
Brand: TargetMol
SKU: T16424
Price: 190 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T16424Cas号 1006378-90-0

p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).

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p38 MAPK-IN-1

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产品编号 T16424Cas号 1006378-90-0

p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).

规格	价格	库存
2 mg	¥ 1,890	5日内发货
5 mg	¥ 2,890	5日内发货
25 mg	¥ 9,620	8-10周
50 mg	¥ 12,500	8-10周
100 mg	¥ 17,500	8-10周
1 mL x 10 mM (in DMSO)	¥ 3,180	5日内发货

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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
靶点活性	p38 MAPK:68 nM
体内活性	p38 MAPK-IN-1 dose-dependently inhibits TNFα production (ED50: 0.5 mg/kg). p38 MAPK-IN-1 (1 mg/kg for iv and 10 mg/kg for p.o.) has a t1/2 of 7.4 hours and CL of 2.7 mL/min/kg for iv, and a Cmax of 5.3 μM for p.o. in male wistar rats[1].

化学信息

分子量	348.35
分子式	C₂₁H₁₄F₂N₂O
CAS No.	1006378-90-0
密度	1.27 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 8.33 mg/mL (23.84 mM), Sonication is recommended.

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	2.8707 mL	14.3534 mL	28.7068 mL	143.5338 mL
5 mM	0.5741 mL	2.8707 mL	5.7414 mL	28.7068 mL
10 mM	0.2871 mL	1.4353 mL	2.8707 mL	14.3534 mL
20 mM	0.1435 mL	0.7177 mL	1.4353 mL	7.1767 mL